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Weight Management
Weight Management

When Does Ozempic Start Working?

Danielle Matthies, RD, LD, CD
Author: 
Medical Reviewer: 
Danielle Matthies, RD, LD, CD
|
Author: 
Heather Smith, RN, BSN
Published:
June 13, 2024
Updated on
#
min read
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Table of Contents

Text Link
Weight Management

Key Takeaways

  • Ozempic (semaglutide) is a medication that helps with weight loss and blood sugar control in adults with type 2 diabetes.
  • It can take several weeks after starting the medication before noticeable changes begin to occur.
  • Consulting with a Nourish dietitian can help you develop a personalized nutrition plan to help you achieve your health goals.

Ozempic is a convenient once-weekly injection medication to help you manage your blood sugar levels and achieve weight loss. 

The medication stimulates insulin secretion from the pancreas, slows the rate of digestion, and decreases the amount of glucagon (sugar) the liver releases to help stabilize blood sugar levels.  

When going into something new, like starting a medication, it’s nice to have a timeline of when you can expect to see changes. 

Initially, your medical provider will start you on a smaller dose to help your body adjust to the medication, and after several weeks, you’ll transition to the regular dose. 

You may notice some changes to your blood sugar control at first, but it may take a few weeks before seeing significant changes. 

Read on for more details about when you can expect to experience changes from Ozempic.

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When Does Ozempic Start Working?

Ozempic starts to work in your body when you take your first dose.

However, because the medication is long-acting, the effects on your blood sugar and weight can take several weeks.

According to the manufacturer’s dosing instructions, your medical provider will start you at a dose of 0.25 mg.

After four weeks, they’ll increase the dose to 0.5 mg weekly and then decide if the dose needs to increase more. 

If you are experiencing side effects like nausea, vomiting, or changes to your bowel habits, your medical provider may slow your progression.

Overall, it can take 16 weeks or more to reach the maximum dose of 2 mg.

However, each person responds differently to the medication, so your timeline may be unique to you.

When starting Ozempic, it’s good to have a realistic expectation that patience is key.

How Long Does It Take To Lose Weight On Ozempic?

Losing weight on Ozempic varies from person to person and typically does not start immediately.  

Some people may start to lose weight in the first few weeks, while for others, it may take around eight weeks to notice a difference.

Personal factors such as your age, genetics, health history, and lifestyle factors like your diet and exercise habits all play a role in your weight loss timeline.

It’s important to understand that Ozempic works alongside a balanced diet and regular physical activity. 

If you’re unsure how to eat while taking Ozempic, a Nourish dietitian would be a huge help. 

Will My Weight Loss Plateau While Taking Ozempic?

It’s normal to go through different stages of weight loss while taking Ozempic, including experiencing a plateau.

When you start losing weight on Ozempic, you may notice a steady and consistent decrease over a period of time.

However, you may notice that your weight loss slows down after a while or comes to a complete halt. This is normal and OK.

At this time, it may be a good idea to check back in with your Nourish dietitian.

You both can review your eating habits and how much exercise you’ve been getting and look into other aspects of your life, like stress levels and sleep patterns, which can also affect weight loss.

You may find some areas you can change to support a healthy metabolism.

It’s also a good idea to have other methods of tracking your progress.

The number on the scale is just one aspect and does not differentiate between fat, water, and muscle. 

Some other ways to track progress can include:

  • Taking measurements of your upper arms, waist, hips, and thighs.
  • Tracking improvements in your physical performance.
  • Keeping a photo journal of your progress.
  • Seeing changes in how your clothes fit.
  • Tracking improvements in your blood sugar.

While hitting a plateau can be frustrating, keep in mind that this journey is about improving your overall wellness and not just hitting a goal number on a scale.

What To Expect When Starting Ozempic

Like all medications, when starting Ozempic, your body will go through a time of adjusting to the medication. 

Here are some things to expect.

Common Side Effects

All medications come with the possibility of causing side effects.

For Ozempic, the most common side effects include:

  • Nausea.
  • Vomiting.
  • Diarrhea.
  • Stomach pain.
  • Constipation.

About 5% of people taking Ozempic experience one or more of these side effects.

They typically are mild, however, and tend to diminish over time.

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Adjusting To The Medication

As your body adjusts to the medication during the first few weeks of treatment, it’s good to communicate how you feel with your provider.

If your side effects are too severe or affect your ability to perform your daily tasks, they may reduce your dose and slow your progression.

Some people do not tolerate Ozempic well and need to choose another option for blood sugar management.

Monitoring Progress

It’s important to keep track of your blood sugar levels when you start Ozempic.

Over time, you’ll start to notice changes, which will help your doctor determine the correct dose for you. 

Tips To Maximize Ozempic’s Effectiveness

To maximize the effectiveness of Ozempic, consider following these tips:

  • Be consistent: It’s crucial that you remain consistent with your medication dose and take it on the same day and at the same time each week. 
  • Eat a balanced diet: Although you may feel less hungry, it’s important that the food you eat works with Ozempic and meets your nutritional needs. 
  • Exercise regularly: Join a pickleball group, take up dancing, or ask a friend to walk with you. Make sure to get 30 minutes of moderate physical activity five days a week, along with resistance training. 

Safety Precautions And Considerations

Before starting Ozempic, it’s important that you discuss your medical history, medications, and supplements with your doctor to avoid potential interactions and contraindications.

If you have a family history of thyroid cancer or have had pancreatitis, it’s best to discuss other options for managing your blood sugar or weight with your doctor. 

Takeaway

Ozempic can be an effective medication for blood sugar control and weight loss, but it may take several weeks for you to see results. 

Initially, your doctor will start you on a smaller dose to give your body time to adjust to the new medication.

Depending on how you tolerate it, your doctor may increase your dose over several months until you reach the maximum dose. 

To get the most out of Ozempic, it’s important to remain consistent with your weekly injection and take it on the same day and at the same time.

It’s also crucial to eat a balanced diet and get regular exercise.

As with all weight loss journeys, there is a possibility of hitting a weight loss plateau.

With some reevaluation and a look at other measurements of improvement, you can keep moving ahead on your journey to better health.

{{splash}}

How A Dietitian Can Help

For more detailed guidance on how your diet contributes to the effectiveness of Ozempic, consider talking with a Nourish dietitian. 

They are experts in the area of diet for weight loss and blood sugar management, and after talking with them, you can develop an eating plan that fits your unique needs and goals. 

Equipped with a wealth of knowledge, your dietitian can also help you learn strategies for overcoming side effects or managing weight loss plateaus.

By learning and implementing new behaviors surrounding food, you can maximize the effectiveness of Ozempic and make changes to your health that last a lifetime.

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Frequently Asked Questions

How long does it take Ozempic to work for weight loss?

The time frame for weight loss with Ozempic can vary for each individual.

While some people may start to see weight changes early on, it’s best to have the expectation that it will take eight weeks or more to see changes.

How fast do symptoms of Ozempic start?

The side effects of Ozempic may start within the first few days of your initial treatment.

Common side effects include nausea, vomiting, stomach pain, diarrhea, and constipation.

Over time these symptoms may decrease as your body adjusts to the medication.

How do you lose weight fast on Ozempic?

To enhance the effectiveness of Ozempic, it’s important to follow a balanced diet and get regular exercise.

It’s also crucial to remain consistent with the medication schedule. 

However, it’s necessary to have the realistic expectation that weight loss with Ozempic may not start right away and can be a gradual process.

‍

References

View all references

Ozempic Semaglutide Injection. (N.D.) NOVOMEDLINK Website.

Ozempic Semaglutide. (2023). Prescribing Information PDF.

About Healthy Weight and Growth. (2024). CDC.

‍What You Can Do to Meet Physical Activity Recommendations. (2024). CDC.

Nourish has strict sourcing policies and prioritizes primary sources, including medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about our medical review process and editorial guidelines.

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, 
FL
Florida
25.857595, -80.278107
Springfield
, 
MA
Massachusetts
42.102051, -72.585762
Toledo
, 
OH
Ohio
41.652805, -83.537865
Pembroke Pines
, 
FL
Florida
26.007765, -80.296257
Overland Park
, 
KS
Kansas
38.974819, -94.683601
Little Rock
, 
AR
Arkansas
34.746483, -92.289597
Glendale
, 
CA
California
34.142509, -118.255074
Roseville
, 
CA
California
38.752125, -121.288010
Rancho Cucamonga
, 
CA
California
,
Wichita
, 
KS
Kansas
37.687176, -97.330055
Huntington Beach
, 
CA
California
33.659485, -117.998802
Augusta
, 
GA
Georgia
33.4709714, -81.9748429
Worcester
, 
MA
Massachusetts
42.271389, -71.798889
Virginia Beach
, 
VA
Virginia
36.852924, -75.977982
Oceanside
, 
CA
California
33.1958696, -117.3794834
Santa Clarita
, 
CA
California
34.456043, -118.571335
Philadelphia
, 
PA
Pennsylvania
39.952583, -75.165222
Corpus Christi
, 
TX
Texas
27.800583, -97.396378
Portland
, 
OR
Oregon
45.512230, -122.658722
Denver
, 
CO
Colorado
39.739235, -104.990250
Boston
, 
MA
Massachusetts
42.3554334, -71.060511
Atlanta
, 
GA
Georgia
33.7489924, -84.3902644
Chicago
, 
IL
Illinois
41.8755616, -87.6244212
Orlando
, 
FL
Florida
28.538336, -81.379234
Jacksonville
, 
FL
Florida
30.332184, -81.655647
Tampa
, 
FL
Florida
27.950575, -82.457176
Long Island
, 
NY
New York
40.757801, -73.940033
Queens
, 
NY
New York
40.728226, -73.794853
Bronx
, 
NY
New York
40.8466508, -73.8785937
Staten Island
, 
NY
New York
40.643501, -74.076202
Brooklyn
, 
NY
New York
40.6526006, -73.9497211
New York
, 
NY
New York
40.712776, -74.005974
San Jose
, 
CA
California
37.342205, -121.851990
San Francisco
, 
CA
California
37.774929, -122.419418
San Diego
, 
CA
California
32.834686, -117.130775
Los Angeles
, 
CA
California
34.052235, -118.243683
El Paso
, 
TX
Texas
31.761877, -106.485023
San Antonio
, 
TX
Texas
29.387428, -98.496574
Dallas
, 
TX
Texas
32.776665, -96.796989
Fort Worth
, 
TX
Texas
32.755489, -97.330765
Houston
, 
TX
Texas
29.760427, -95.369804
Austin
, 
TX
Texas
30.2711286, -97.7436995
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